HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenepropanol → 5-Bromo-4-furan-2-yl-6-(3-phenyl-propoxy)-pyrimidin-2-yl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenepropanol | HCID 31234 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 5-Bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-ylamine | HCID 18507286 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-Bromo-4-furan-2-yl-6-(3-phenyl-propoxy)-pyrimidin-2-yl-amine | HCID 9969609 | — |
Reaction Steps
From 5-bromo-4-furan-2-yl-6-methanesulfinyl-pyrimidin-2-yl-amine, 3-phenyl-1-propanol and DBU in dioxane. ES-MS m/e (%): 376 (M{81Br}+H+, 98), 374 (M{79Br}+H+, 100), 258 ([M{81Br}+H-BnCH═CH2]+, 55), 256 ([M{81Br}+H-BnCH ═CH2]+, 50).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-82f0df81fe73476094c290d1b45cbe35 |
| Source note | uspto-grants-2003_07 |