Phenethyl bromide → HCID 18507500, compound

HRID 1355910Notes

Reaction equation

HRID 1355910 reaction equation
[NH2:1][C:2]1[NH:7][C:6](=[S:8])[C:5]([C:9]#[N:10])=[C:4]([C:11]2[O:12][CH:13]=[CH:14][CH:15]=2)[C:3]=1[C:16]#[N:17].[C:18]1([CH2:24][CH2:25]Br)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C[O-].[Na+]>CO>[NH2:1][C:2]1[C:3]([C:16]#[N:17])=[C:4]([C:11]2[O:12][CH:13]=[CH:14][CH:15]=2)[C:5]([C:9]#[N:10])=[C:6]([S:8][CH2:25][CH2:24][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:7]=1

Participants

5

Reactant 3

HCID 7666Phenethyl bromideHCID 764895HCID 764895, compoundHCID 10942334Sodium Methoxide

Product 1

HCID 18507500HCID 18507500, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

From 6-Amino-4-furan-2-yl-2-thioxo-1,2-dihydro-pyridine-3,5-dicarbonitrile, 2-phenylethyl bromide and sodium methylate in methanol. EI-MS m/e (%): 346 (M+, 4), 242 ([M—PhCH═CH2]+, 100), 91 (16).

Sources & evidence

ORD record
ord-69081a5c47804a2f8628c471b0f60d92
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…