Benzylamine → 2-Amino-4-benzylamino-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile

HRID 1355919Notes

Reaction equation

HRID 1355919 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([C:13]2[O:14][C:15]([CH3:18])=[CH:16][CH:17]=2)[N:3]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([NH:26][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:5]([C:11]#[N:12])=[C:4]([C:13]2[O:14][C:15]([CH3:18])=[CH:16][CH:17]=2)[N:3]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 185074622-Amino-4-methanesulfinyl-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile

Product 1

HCID 99662642-Amino-4-benzylamino-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-(5-methyl-furan-2-yl)-pyrimidine-5-carbonitrile and benzylamine in DME. ES-MS m/e (%): 306 (M+H+, 100).

Sources & evidence

ORD record
ord-0315d2427af4494cb04ea9fce0fd88bf
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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