Phenyl-2-aminoethyl sulfide → 2-Amino-4-furan-2-yl-6-(2-phenylsulfanyl-ethylamino)-pyrimidine-5-carbonitrile

HRID 1355973Notes

Reaction equation

HRID 1355973 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[C:18]1([S:24][CH2:25][CH2:26][NH2:27])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([NH:27][CH2:26][CH2:25][S:24][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:3]=1

Participants

4

Reactant 2

HCID 37013Phenyl-2-aminoethyl sulfideHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 185075262-Amino-4-furan-2-yl-6-(2-phenylsulfanyl-ethylamino)-pyrimidine-5-carbonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and 2-aminoethyl phenyl sulfide in DME. ES-MS m/e (%): 338 (M+H+, 100).

Sources & evidence

ORD record
ord-2173c114bb9c4dfab388a4bf6fe741e1
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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