HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-[2-(4-chloro-phenylamino)-ethylamino]-6-furan-2-yl-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile | HCID 18507692 | — |
| Reactant | N-(p-chlorophenyl)ethylenediamine maleate | HCID 69783430 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-[2-(4-chloro-phenylamino)-ethylamino]-6-furan-2-yl-pyrimidine-5-carbonitrile | HCID 18507681 | — |
Reaction Steps
From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, N-(p-chlorophenyl)ethylenediamine maleate and DBU in DME. ES-MS m/e (%): 357 (M{37Cl}+H+, 40), 355 (M{35Cl}+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-129b0c6da184478ea064749c669d476d |
| Source note | uspto-grants-2003_07 |