1,2,3,4-Tetrahydroisoquinoline → HCID 9836612, compound

HRID 1356004Notes

Reaction equation

HRID 1356004 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[CH2:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:21][CH2:20][NH:19]1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([N:19]2[CH2:20][CH2:21][C:22]3[C:27](=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:18]2)[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[N:7]=1

Participants

4

Reactant 2

HCID 70461,2,3,4-TetrahydroisoquinolineHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 9836612HCID 9836612, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and 1,2,3,4-tetrahydroisoquinoline in DME. ES-MS m/e (%): 318 (M+H+, 100).

Sources & evidence

ORD record
ord-4a9730c6e8694d68a98bd5e1485be015
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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