4-(Trifluoromethoxy)benzylamine → HCID 18507514, compound

HRID 1356006Notes

Reaction equation

HRID 1356006 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.[F:18][C:19]([F:30])([F:29])[O:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25][NH2:26])=[CH:23][CH:22]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([NH:26][CH2:25][C:24]2[CH:27]=[CH:28][C:21]([O:20][C:19]([F:18])([F:29])[F:30])=[CH:22][CH:23]=2)[N:3]=1

Participants

4

Reactant 2

HCID 5718464-(Trifluoromethoxy)benzylamineHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

Product 1

HCID 18507514HCID 18507514, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and 4-(trifluoromethoxy)benzylamine in DME. ES-MS m/e (%): 376 (M+H+, 100).

Sources & evidence

ORD record
ord-71f689a4065e4d82be9efcdf75cf68e4
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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