HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-(Trifluoromethyl)pyridin-2-yl]methanamine → 2-Amino-4-furan-2-yl-6-[(5-trifluoromethyl-pyridin-2-yl-methyl)-amino]-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-(Trifluoromethyl)pyridin-2-yl]methanamine | HCID 3796375 | — |
| Reactant | 2-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile | HCID 18507692 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-furan-2-yl-6-[(5-trifluoromethyl-pyridin-2-yl-methyl)-amino]-pyrimidine-5-carbonitrile | HCID 18507348 | — |
Reaction Steps
From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile and C-(5-trifluoromethyl-pyridin-2-yl)-methylamine in DME. ES-MS m/e (%): 361 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-fbbb571d945e4e2da2ce9e0dff6087b7 |
| Source note | uspto-grants-2003_07 |