Benzylamine → 2-Amino-4-benzylamino-6-pyridin-2-yl-pyrimidine-5-carbonitrile

HRID 1356099Notes

Reaction equation

HRID 1356099 reaction equation
[NH2:1][C:2]1[N:7]=[C:6](S(C)=O)[C:5]([C:11]#[N:12])=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[N:3]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([NH:26][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:5]([C:11]#[N:12])=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[N:3]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 185076952-Amino-4-methanesulfinyl-6-pyridin-2-yl-pyrimidine-5-carbonitrile

Product 1

HCID 185076032-Amino-4-benzylamino-6-pyridin-2-yl-pyrimidine-5-carbonitrile

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

From 2-amino-4-methanesulfinyl-6-pyridin-2-yl-pyrimidine-5-carbonitrile and benzylamine in DME. ES-MS m/e (%): 303 (M+H+, 100).

Sources & evidence

ORD record
ord-b794b28078c24904ae2fec35bd360a43
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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