HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-(3,5-dimethyl-pyridin-2-yl-methoxy)-6-pyridin-2-yl-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | (3,5-Dimethylpyridin-2-yl)methanol | HCID 10630548 | — |
| Reactant | 2-Amino-4-methanesulfinyl-6-pyridin-2-yl-pyrimidine-5-carbonitrile | HCID 18507695 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-(3,5-dimethyl-pyridin-2-yl-methoxy)-6-pyridin-2-yl-pyrimidine-5-carbonitrile | HCID 18507663 | — |
Reaction Steps
From 2-amino-4-methanesulfinyl-6-pyridin-2-yl-pyrimidine-5-carbonitrile, 3,5-dimethyl-2-pyridinemethanol and DBU in DME. EI-MS m/e (%): 332 (M+, 100), 303 (34), 120 (31).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-6c792d861ced45a9a9c135ead09bb793 |
| Source note | uspto-grants-2003_07 |