HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanediamine, N1-phenyl- → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanediamine, N1-phenyl- | HCID 74270 | — |
| Reactant | Trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester | HCID 86583757 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile | HCID 18507471 | — |
Reaction Steps
From trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester and N-phenylethylenediamine in DME. ES-MS m/e (%): 323 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-3044f3acc88542069d19f21a1000a70a |
| Source note | uspto-grants-2003_07 |