HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(pyridin-2-yl-methoxy)-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Picolyl chloride hydrochloride | HCID 23392 | — |
| Reactant | 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile | HCID 135724996 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(pyridin-2-yl-methoxy)-pyrimidine-5-carbonitrile | HCID 18507259 | — |
Reaction Steps
From 2-amino-4-(4,5-dihydro-furan-2-yl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile, 2-picolyl chloride hydrochloride and caesium carbonate in DMF. ES-MS m/e (%): 296 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-38c2b32f1187499fa6728dafcfcee7be |
| Source note | uspto-grants-2003_07 |