HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piconol → 2-Amino-4-chloro-6-(pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piconol | HCID 11474 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 2-Amino-4-chloro-6-methanesulfinyl-pyrimidine-5-carbonitrile | HCID 18507277 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Amino-4-chloro-6-(pyridin-2-ylmethoxy)-pyrimidine-5-carbonitrile | HCID 18507485 | — |
Reaction Steps
From 2-amino-4-chloro-6-methanesulfinyl-pyrimidine-5-carbonitrile, 2-(hydroxymethyl)pyridine and DBU in DME. EI-MS m/e (%): 261 (M+, 75), 184 (46), 108 (95), 92 (100), 65 (70), 39 (45).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586441B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-25469420cdf04868a0914c1335b7d865 |
| Source note | uspto-grants-2003_07 |