HCID 22396798, compound → HCID 22396816, compound

HRID 1356360Notes

Reaction equation

HRID 1356360 reaction equation
Cl.[Cl:2]C1C=CC(C2C3C4CCNCCC=4NC=3C=CC=2)=CC=1.C([N:31]1[CH2:44][CH2:43][C:42]2[C:41]3[C:40]([C:45]4[CH:50]=[CH:49][CH:48]=[C:47]([Cl:51])[CH:46]=4)=[CH:39][CH:38]=[CH:37][C:36]=3[NH:35][C:34]=2[CH2:33][CH2:32]1)(=O)C1C=CC=CC=1>>[ClH:2].[ClH:51].[Cl:51][C:47]1[CH:46]=[C:45]([C:40]2[C:41]3[C:42]4[CH2:43][CH2:44][NH:31][CH2:32][CH2:33][C:34]=4[NH:35][C:36]=3[CH:37]=[CH:38][CH:39]=2)[CH:50]=[CH:49][CH:48]=1

Participants

3

Reactant 2

HCID 22396798HCID 22396798, compoundHCID 22396865HCID 22396865, compound

Product 1

HCID 22396816HCID 22396816, compound

Procedure

Following the procedure for the preparation of 10-(4-chlorophenyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole hydrochloride, making non-critical variations, starting with 3-benzoyl-10-(3-chlorophenyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole, the title compound was obtained. 1H NMR (DMSO-d6) δ 3.05, 3.21, 3.31, 4.51, 6.85, 7.1-7.5, 11.3.

Sources & evidence

ORD record
ord-a2a2cedd3ea74dbc90d0e2c052f846d0
Source dataset
uspto-grants-2003_07
Patent number
US06586421B2

Reaction notes

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