HCID 22609212, compound → HCID 69896923, compound

HRID 1356377Notes

Reaction equation

HRID 1356377 reaction equation
Cl.Cl.ClC1C=CC(C2C3C4CCNCCC4NC=3C=CC=2)=CC=1.[C:24]1([CH2:30][CH2:31][C:32]2[C:33]3[C:34]4[CH2:45][CH2:44][NH:43][CH2:42][CH2:41][C:35]=4[NH:36][C:37]=3[CH:38]=[CH:39][CH:40]=2)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[C:24]1([CH2:30][CH2:31][C:32]2[C:33]3[C@@H:34]4[CH2:45][CH2:44][NH:43][CH2:42][CH2:41][C@@H:35]4[NH:36][C:37]=3[CH:38]=[CH:39][CH:40]=2)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 22609212HCID 22609212, compoundHCID 22609214HCID 22609214, compound

Product 1

HCID 69896923HCID 69896923, compound

Procedure

Following the procedure for the preparation of 10-(4-chlorophenyl)-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole dihydrochloride, making non-critical variations, starting from 10-(2-phenylethyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole the title compound was prepared: 1H NMR (CDCl3) δ 2.02, 2.14, 2.31, 2.79, 2.88, 2.97, 3.15, 3.64, 4.18, 6.52, 6.70, 7.07, 7.16, 7.21, 7.27, 9.5-9.7. HRMS (FAB) calcd for C20H24N2 (MH+) 293.2018, found 293.2013.

Sources & evidence

ORD record
ord-4f9e95710eb548a4bd7a0fb62aab4ecd
Source dataset
uspto-grants-2003_07
Patent number
US06586421B2

Reaction notes

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