HCID 22396585, compound → HCID 69896244, compound

HRID 1356379Notes

Reaction equation

HRID 1356379 reaction equation
Cl.Cl.ClC1C=CC(C2C3C4CCNCCC4NC=3C=CC=2)=CC=1.[O:24]([CH2:31][CH2:32][CH2:33][C:34]1[C:35]2[C:36]3[CH2:47][CH2:46][NH:45][CH2:44][CH2:43][C:37]=3[NH:38][C:39]=2[CH:40]=[CH:41][CH:42]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[O:24]([CH2:31][CH2:32][CH2:33][C:34]1[C:35]2[C@@H:36]3[CH2:47][CH2:46][NH:45][CH2:44][CH2:43][C@@H:37]3[NH:38][C:39]=2[CH:40]=[CH:41][CH:42]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 22396585HCID 22396585, compoundHCID 22609212HCID 22609212, compound

Product 1

HCID 69896244HCID 69896244, compound

Procedure

Following the procedure for the preparation of 10-(4-chlorophenyl)-1,2,3,4,5,5a,6,10b-octahydroazepino[4,5-b]indole dihydrochloride, making non-critical variations, starting from 10-(3-phenoxypropyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole the title compound was prepared: 1H NMR (CDCl3) δ 2.02-2.14, 2.27, 2.74, 2.90-3.03, 3.45, 3.50, 3.98, 4.14, 4.50, 6.47, 6.63, 6.91, 6.95, 7.03, 7.30. HRMS (FAB) calcd for C21H26N2O (MH+) 323.2123, found 323.2104.

Sources & evidence

ORD record
ord-75e4d98cfa9148ba97f85938e9deb54b
Source dataset
uspto-grants-2003_07
Patent number
US06586421B2

Reaction notes

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