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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1356449Generated: October 29, 2026

Dipropylamine → HCID 18508366, compound

https://huagongshe.com/reaction/1356449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDipropylamineHCID 8902—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 11439556HCID 11439556—
SolventWaterHCID 962—
SolventDimethylformamideHCID 6228—
ProductHCID 18508366HCID 18508366—

Reaction Steps

To a solution of 3-(4-benzyloxyphenyl)propyl iodide (1.790 g) in DMF (20 ml) were added N,N-dipropylamine (1.3 ml) and potassium carbonate (1.391 g). The reaction mixture was stirred at room temperature for 29 hr, diluted with water, and extracted with ethyl acetate. The residue was purified by silica gel column chromatography (eluent:hexane/ethyl acetate=1/1) to obtain 3-(4-benzyloxyphenyl)propyl-N,N-dipropylamine (1.589 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06586475B1
Source datasetuspto-grants-2003_07
ORD IDord-01155bda771a41cfaa86eed19bf88f14
Source noteuspto-grants-2003_07