HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → methyl (2S)-4-methyl-2-(methylamino)pentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | N-Methylleucine | HCID 2777993 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | methyl (2S)-4-methyl-2-(methylamino)pentanoate | HCID 10921446 | 100% |
Reaction Steps
N-methyl-L-leucine (1.3 g, 8.95 mmol) was dissolved in 4M HCl, 1,4 dioxane (10 mL) and methanol (10 mL). The solution was stirred overnight at room temperature, then concentrated to afford the title compound as a white solid (100%). MS (ESI): 160.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586466B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-c84cddade0974f8e87532868bc68310d |
| Source note | uspto-grants-2003_07 |