HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → (R)-4-cyano-3-hydroxybutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | (r)-4-Cyano-3-hydroxybutyric acid sodium salt | HCID 88064244 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (R)-4-cyano-3-hydroxybutyric acid | HCID 10236005 | — |
Reaction Steps
The reaction mixture containing (R)-4-cyano-3-hydroxy butyric acid sodium salt was acidified to pH 1 with concentrated sulfuric acid. The reaction mixture was condensed, dissolved in ethanol and filtered. The filtrate was concentrated to give (R)-4-cyano-3-hydroxybutyric acid which was used for esterification without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586616B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-dd6563daa63345018ab175c986ce86b1 |
| Source note | uspto-grants-2003_07 |