HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 53635666, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | (R)-4-cyano-3-hydroxybutyric acid | HCID 10236005 | — |
| Product | HCID 53635666 | HCID 53635666 | 90% |
Reaction Steps
(R)-4-cyano-3-hydroxybutyric acid (1.0 mol) in isopropanol (500 ml) and conc. sulfuric acid (5 g) were refluxed for 5 hours. The reaction mixture was neutralized with sodium carbonate and filtered. The filtrate was concentrated in vacuo to afford (R)-4-cyano-3-hydroxybutyric acid isopropyl ester (163 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586616B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-42b1f379ddb04583a6843fa792cdf455 |
| Source note | uspto-grants-2003_07 |