HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 11217654, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isobutanol | HCID 6560 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | (R)-4-cyano-3-hydroxybutyric acid | HCID 10236005 | — |
| Product | HCID 11217654 | HCID 11217654 | 92% |
Reaction Steps
(R)-4-cyano-3-hydroxybutyric acid (1.0 mol) in isobutanol (500 ml) and conc. sulfuric acid (5 g) were refluxed for 5 hours. The reaction mixture was neutralized with sodium carbonate and filtered. The filtrate was concentrated in vacuo to afford (R)-4-cyano-3-hydroxybutyric acid isobutyl ester (157 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586616B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-6b900cb04af646aab78a088469a348af |
| Source note | uspto-grants-2003_07 |