Glyoxylic Acid → Disodium

HRID 1356586Notes

Reaction equation

HRID 1356586 reaction equation
[S:1](S([O-])=O)([O-:3])=[O:2].[Na+:7].[Na+:8].[C:9]([OH:13])(=[O:12])[CH:10]=[O:11].[OH-].[Na+]>O>[OH:11][CH:10]([S:1]([O-:3])=[O:2])[C:9]([OH:13])=[O:12].[Na:7][Na:8]

Participants

6

Reactant 3

HCID 760Glyoxylic AcidHCID 14798Sodium HydroxideHCID 24489Sodium Dithionite

Product 2

HCID 141233DisodiumHCID 211332982-Hydroxy-2-sulfinatoacetic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The reaction of 358 g of commercially available sodium hydrosulfite in 800 ml of water with 268 g of 50% strength glyoxylic acid and 285 g of 50% sodium hydroxide solution gave the 2-hydroxy-2-sulfinatoacetic acid, disodium salt in a yield of 95%. The solid crude product contained 43% of sulfinic acid (without water of hydration). Crystallization from a methanol/ethanol/water mixture gave the hydrate of the sulfinic acid in nice crystals. The sulfur-containing constituents were determined using iodometry. The sulfinic acid shows a reaction with indanthrene paper at about 75° C.

Sources & evidence

ORD record
ord-e782fba0008c4b4c9736caee4a944cd6
Source dataset
uspto-grants-2003_07
Patent number
US06586622B2

Reaction notes

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