Nitric Acid → HCID 18509253, compound

Participants

Reaction Steps

To a suspension of 2′-cyano-p-toluenesulfonanilide (2.67g (9.80 mmol) in acetic anhydride (7.0 ml), 97% fuming nitric acid (0.45 ml (10.5 mmol) was added with stirring at room temperature. After stirring for one hour at 50° C., crystals began to separate. Water was added to decompose excess acetic anhydride, and the crystals were filtered, washed with water, dried in the air and then, washed with diethyl ether and collected by filtration to give 3.05 g (98%) of 2′-cyano-4′-nitro-p-toluenesulfonanilide as pale yellow crystals.

Provenance & Evidence