Chloroacetyl chloride → 3-Methyl-4-isopropylphenyl chloroacetate

HRID 1356709Notes

Reaction equation

HRID 1356709 reaction equation
[Cl:1][CH2:2][C:3](Cl)=[O:4].[CH3:6][C:7]1[CH:8]=[C:9]([OH:16])[CH:10]=[CH:11][C:12]=1[CH:13]([CH3:15])[CH3:14]>>[Cl:1][CH2:2][C:3]([O:16][C:9]1[CH:10]=[CH:11][C:12]([CH:13]([CH3:14])[CH3:15])=[C:7]([CH3:6])[CH:8]=1)=[O:4]

Participants

3

Reactant 2

HCID 6577Chloroacetyl chlorideHCID 185973-Methyl-4-isopropylphenol

Product 1

HCID 120842613-Methyl-4-isopropylphenyl chloroacetate

Procedure

By the same method of Synthesis Example 6, chloroacetyl chloride was allowed to react with 3-methyl-4-isopropylphenol, the reaction mixture was washed with water and then the solvent was evaporated under a reduced pressure to obtain the title compound as a transparent oil. The title compound was used in the subsequent reaction without distillation.

Workup

  1. washthe reaction mixture was washed with water
  2. customthe solvent was evaporated under a reduced pressure

Sources & evidence

ORD record
ord-8bc2b48361ca4f2fbf6baf343434a6d3
Source dataset
uspto-grants-2003_07
Patent number
US06586639B2

Reaction notes

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