HCID 131723963, compound → HCID 131723962, compound

Participants

Reaction Steps

To a solution of Fmoc-Phe-N-Me-Val-Tyr(3-NMe2)—NH2 (163 mg, 0.227 mmol) in methylene chloride (1.5 ml), diethylamine (1 ml) was added, followed by stirring at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure; the thus obtained residue was subjected to silica gel column chromatography (developing solvent: chloroform:methanol:aqueous ammonia=10:1:0.1) to give the titled compound (91.2 mg, 81%).

Provenance & Evidence