HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → trans-N-Cyclopropyl-N-(6,6-dimethyl-2-hepten-4-ynyl)-(3-isopropenylbenzyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | trans-3'-[N-Cyclopropyl-N-(6,6-dimethyl-2-hepten-4-ynyl)aminomethyl]acetophenone | HCID 18509435 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Catalyst | Methyltriphenyliphosphonium bromide | HCID 74505 | — |
| Product | trans-N-Cyclopropyl-N-(6,6-dimethyl-2-hepten-4-ynyl)-(3-isopropenylbenzyl)amine | HCID 18509418 | 45.6% |
Reaction Steps
The procedure described in Example 9 was repeated, except that methyl triphenylphosphonium bromide (0.57 g; 1.61 mmol), n-butyl lithium in n-hexane (1.56 M: 1.0 ml; 1.61 mmol), and Compound 13 (0.33 g; 1.07 mmol) were used, to thereby yield 0.15 g of the target compound (yield: 45.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586633B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-b2a0caa7192040fc8bbd41f34ac8cf34 |
| Source note | uspto-grants-2003_07 |