HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-ethyl-(3-isopropenylbenzyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | trans-3'-[N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-ethylaminomethyl]acetophenone | HCID 18509427 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Catalyst | Methyltriphenyliphosphonium bromide | HCID 74505 | — |
| Product | trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-ethyl-(3-isopropenylbenzyl)amine | HCID 18509410 | 73.6% |
Reaction Steps
The procedure described in Example 9 was repeated, except that methyl triphenylphosphonium bromide (2.35 g; 6.6 mmol), n-butyl lithium in n-hexane (1.56 M: 4.2 ml; 6.6 mmol), and Compound 43 (1.3 g; 4.4 mmol) were used, to thereby yield 950 mg of the target compound (yield: 73.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586633B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-00d3a23a393143218026f73dfbcb4a1e |
| Source note | uspto-grants-2003_07 |