HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → N-(4-tert-Butylbenzyl)-N-cyclopropyl-(3-isopropenylbenzyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 3'-[N-(4-tert-Butylbenzyl)-N-cyclopropylaminomethyl]acetophenone | HCID 18509530 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Catalyst | Methyltriphenyliphosphonium bromide | HCID 74505 | — |
| Product | N-(4-tert-Butylbenzyl)-N-cyclopropyl-(3-isopropenylbenzyl)amine | HCID 18509396 | 35.2% |
Reaction Steps
The procedure described in Example 60 was repeated, except that methyl triphenylphosphonium bromide (0.32 g; 8.94×10−1 mmol), n-butyl lithium in n-hexane (1.56 M: 0.6 ml; 8.9×10−1 mmol), and Compound 82 (0.20 g; 5.96×10−1 mmol) were used, to thereby yield 0.07 g of the target compound (yield: 35.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06586633B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-e16dfbd8cde7441ab5bf3681f7e2ace7 |
| Source note | uspto-grants-2003_07 |