Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1356876Generated: October 26, 2026

Phenylalanine ethyl ester → (S)-2-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid

https://huagongshe.com/reaction/1356876

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylalanine ethyl esterHCID 76506—
Reactant(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carboxylic AcidHCID 6559079—
Product(S)-2-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acidHCID 984756245%

Reaction Steps

3,5-Dichlorophenyl-sulfonyl-L-proline was coupled to L-phenylalanine ethyl ester using the procedure described in Method 3 to give the ethyl ester of the title compound (348 mg, 45%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06586602B2
Source datasetuspto-grants-2003_07
ORD IDord-50d60fb3c2f34950921cf3a14289d0bf
Source noteuspto-grants-2003_07