HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Pyridalyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,1,3-Trichloropropene | HCID 17378 | — |
| Reactant | 3,5-Dichloro-4-[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]propoxy]phenol | HCID 18504557 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Pyridalyl | HCID 11488729 | 47% |
Reaction Steps
A mixture of 0.5 g of 3,5-dichloro-4-[3-(5-trifluoromethylpyridin-2-yloxy)propyloxy]phenol, 0.25 g of 1,1,3-trichloropropene, 0.2.g of potassium carbonate and 3 ml of N,N-dimethylformamide was stirred at room temperature overnight. The reaction mixture was subjected to silica gel chromatography, which afforded 0.3 g of 3,5-dichloro-1-(3,3-dichloro-2-propenyloxy)-4-[3-(5-trifluoromethylpyridin-2-yloxy)propyloxy]benzene (47% yield), nD20.5 1.5377.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06589914B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-a3e695bf037f405ab287eabd154b8af1 |
| Source note | uspto-grants-2003_07 |