Acetamide, N-ethyl-N-(4-nitrophenyl)- → Acetamide, N-(4-aminophenyl)-N-ethyl-

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Reaction Steps

N-acetyl-N-ethyl-4-nitroaniline (9a) (1.8 g, 8.64 mmol) is hydrogenated in THF (30 ml), over 10%Pd on carbon (100 mg) for 1.5 hours. The catalyst is removed by filtration and the solvent removed evaporation. The product crystalises on standing in hexane, and following filtration, is dried under vacuum; ES+ (M+1) 178.88.

Provenance & Evidence