HCID 18504811, compound → HCID 18504827, compound

HRID 1357011Notes

Reaction equation

HRID 1357011 reaction equation
[CH:1]1([O:6][C:7]2[C:8]([O:22][CH3:23])=[CH:9][C:10]([CH:20]=[O:21])=[C:11]([CH:19]=2)[C:12]([N:14]([CH2:17][CH3:18])[CH2:15][CH3:16])=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:24]([Mg]Br)[CH3:25]>>[CH2:15]([N:14]([CH2:17][CH3:18])[C:12](=[O:13])[C:11]1[CH:19]=[C:7]([O:6][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5]2)[C:8]([O:22][CH3:23])=[CH:9][C:10]=1[CH:20]([OH:21])[CH2:24][CH3:25])[CH3:16]

Participants

3

Reactant 2

HCID 18504811HCID 18504811, compoundHCID 178418443HCID 178418443, compound

Product 1

HCID 18504827HCID 18504827, compoundYield 76%

Procedure

Operating analogously to example 31 using 5-cyclopentyloxy-N,N-diethyl-2-formyl-4-methoxy-benzamide, obtained as described in example 4, product B, and ethyl-magnesium bromide the title product was obtained (yield 76%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-b60fbd4a89af42e381d0212b5dcbebff
Source dataset
uspto-grants-2003_07
Patent number
US06589951B1

Reaction notes

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