2-Phenylbutyryl chloride → Ethyl 3-(3-nitrophenyl)-3-(2-phenylbutyrylamino)-propionate
Reaktionsgleichung
Cl.[NH2:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([N+:16]([O-:18])=[O:17])[CH:11]=1)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:19]1([CH:25]([CH2:29][CH3:30])[C:26](Cl)=[O:27])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[N+:16]([C:12]1[CH:11]=[C:10]([CH:3]([NH:2][C:26](=[O:27])[CH:25]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:29][CH3:30])[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH:15]=[CH:14][CH:13]=1)([O-:18])=[O:17]Komponenten
3
Versuchsvorschrift
Corresponding to Example 3a, 5.0 g of (1b) were acetylated with addition of 2-phenylbutyryl chloride. A white solid was obtained (yield: 6.3 g).
Aufarbeitung
- customA white solid was obtained (yield: 6.3 g)
Quellen und Nachweise
- ORD-Eintrag
- ord-54b4c0203e7f4da293964a86a436f35f
- Quelldatensatz
- uspto-grants-2003_07
- Patentnummer
- US06589972B2
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