HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 69596757, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 69596714 | HCID 69596714 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 69596757 | HCID 69596757 | — |
Reaction Steps
The title compound, light yellow oil, MS: m/e=428.2 (M+H+) and [α]D20=−69.7° (c=0.2770 in chloroform), was prepared by methylation of (2R,5S)-2-{2-[5-(4-fluoro-phenyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-ethyl}-1H-imidazole in accordance with the general method of example 8 (methyl iodide, sodium hydride).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06589978B2 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-81531426058240b0bac8f4a6e52f34b3 |
| Source note | uspto-grants-2003_07 |