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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1357168Generated: November 3, 2026

Aluminium lithium hydride → HCID 10135069, compound

https://huagongshe.com/reaction/1357168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAluminium lithium hydrideHCID 21226445—
ReactantHCID 69596731HCID 69596731—
SolventTetrahydrofuranHCID 8028—
ProductHCID 10135069HCID 10135069—

Reaction Steps

Reduction of (2RS,5RS)-4-[5-(4-fluoro-phenyl)-1-(toluene-4 -sulfonyl)-pyrrolidin-2-yl ]-butyric acid methyl ester with lithium aluminum hydride (1.5 eq.) in THF at RT, aqueous work-up and purification by column chromatography yielded the title compound as a colorless oil, MS: m/e=392.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06589978B2
Source datasetuspto-grants-2003_07
ORD IDord-85a8a19bd45f44d38156a7d1e5136ed7
Source noteuspto-grants-2003_07