HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1357212Generated: October 26, 2026
(Dimethylamino)trimethylstannane → 4-acetyloxy-3,5-dimethyl-6-(6-dimethylaminobenzofuran-2-yl)-2H-pyran-2-one
https://huagongshe.com/reaction/1357212
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (Dimethylamino)trimethylstannane | HCID 101941 | — |
| Reactant | 4-acetyloxy-3,5-dimethyl-6-(6-(trifluoromethanesulfonyloxy) benzofuran-2-yl)-2H-pyran-2-one | HCID 18505731 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-acetyloxy-3,5-dimethyl-6-(6-dimethylaminobenzofuran-2-yl)-2H-pyran-2-one | HCID 18505484 | — |
Reaction Steps
Tetrakis(triphenylphosphine)palladium (3 mg) and dimethylaminotrimethyltin (34 mg) were added to a solution of 4-acetyloxy-3,5-dimethyl-6-(6-(trifluoromethanesulfonyloxy) benzofuran-2-yl)-2H-pyran-2-one (45 mg) in toluene (5 ml), and the mixture was stirred at 50° C. overnight. After cooling, the reaction solution was concentrated under reduced pressure and the residue was purified by silica gel column chromatography (n-hexane/AcOEt=5/1) to obtain 4-acetyloxy-3,5-dimethyl-6-(6-dimethylaminobenzofuran-2-yl)-2H-pyran-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06589984B1 |
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| Source dataset | uspto-grants-2003_07 |
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| ORD ID | ord-96a3a9973c4c40018ef7b40f8ef2d6ae |
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| Source note | uspto-grants-2003_07 |
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