HCID 66954950, compound → (4-Chlorophenyl){3-[2-(thiophen-2-yl)ethenyl]-1H-pyrazol-1-yl}methanone

HRID 1357320Notes

Reaction equation

HRID 1357320 reaction equation
CS([N:5]1[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)=[N:6]1)(=O)=O.[Cl:17][C:18]1[CH:23]=[CH:22][C:21](S(N2C=CC(C=CC3SC=CC=3)=N2)(=O)=O)=[CH:20][CH:19]=1.ClC1C=CC=[C:44]([O:48]C2C=CC(C3C=CN(CC4C=CC(Cl)=CC=4)N=3)=CC=2)C=1C#N.ClC1C=CC(C(N2C=CC(C3N4C=CC=CC4=NC=3C)=N2)=O)=CC=1.ClC1C=CC(NC(N2C=CC(C=CC3SC=CC=3)=N2)=O)=CC=1.C(C1C=CN(C(C2C=CC(Cl)=CC=2)=O)N=1)(C1C=CC=CC=1)C1C=CC=CC=1.ClC1C=CC(C(N2C=CC(C3SC(C4SC(C5SC=CC=5)=CC=4)=NC=3C)=N2)=O)=CC=1.C1(NC(N2C=CC(C=CC3SC=CC=3)=N2)=O)C=CC=CC=1.ClC1C=C(Cl)C=CC=1C(N1C=CC(C2OC(C3C=CC(F)=CC=3F)=CC=2)=N1)=O.ClC1C=CC(C(N2C=CC(C3SC(C4SC=CC=4)=CC=3)=N2)=O)=CC=1.ClC1C=CC(C(N2C=CC(C3C(C4C=CC(Cl)=CC=4)=NOC=3C)=N2)=O)=CC=1.ClC1C=CC(C(N2C=CC(C3ON=C(C4C=CC=CC=4)C=3)=N2)=O)=CC=1.CNC(N1C=CC(C=CC2SC=CC=2)=N1)=O.CC(C)(C)C(N1C=CC(C=CC2SC=CC=2)=N1)=O>>[Cl:17][C:18]1[CH:19]=[CH:20][C:21]([C:44]([N:5]2[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][C:12]3[S:13][CH:14]=[CH:15][CH:16]=3)=[N:6]2)=[O:48])=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 66954950HCID 66954950, compoundHCID 86587371HCID 86587371, compound

Product 1

HCID 66954939(4-Chlorophenyl){3-[2-(thiophen-2-yl)ethenyl]-1H-pyrazol-1-yl}methanone

Procedure

1-(methylsulfonyl)-3-(2-(2-thienyl)vinyl)-1H-pyrazole; 2,2-dimethyl-1-(3-(2-(2-thienyl)vinyl)-1H-pyrazole1-yl)propan1-one N-methyl-3-(2-(2-thienyl)vinyl)-1H-pyrazole-1-carboxamide (4-chlorophenyl)(3-(3-phenylisoxazol-5-yl)-1H-pyrazol-1-yl)methanone (4-chlorophenyl)(3-(3-(4-chlorophenyl)-5-methylisoxazol-4-yl)-1H-pyrazol-1-yl)methanone (4-chlorophenyl)(3-(5-(2-thienyl)-2-thienyl)-1H-pyrazol1-yl)methanone (2,4-dichlorophenyl)(3-(5-(2,4-difluorophenyl)-2-furyl)-1H-pyrazol-1-yl)methanone N1-phenyl-3-(2-(2-thienyl)vinyl)-1H-pyrazole-1-carboxamide (4-chlorophenyl)(3-(2-(5-(2-thienyl)-2-thienyl)-4-methyl-1,3-thiazol-5-yl)-1H-pyrazol-1-yl)methanone (3-benzhydryl-1H-pyrazol-1-yl)(4-chlorophenyl)methanone N1-(4-chlorophenyl)-3-(2-(2-thienyl)vinyl)-1H-pyrazole-1-carboxamide (4-chlorophenyl)(3-(2-methylimidazo(1,2-a)pyridin-3-yl)-1H-pyrazol-1-yl)methanone 2-chloro-6-(4-(1-(4-chlorobenzyl)-1H-pyrazol-3-yl)phenoxy)benzonitrile 1-((4-chlorophenyl)sulfonyl)-3-(2-(2-thienyl)vinyl)-1H-pyrazole

Sources & evidence

ORD record
ord-49d9f1e8a87c4d8eadaf256b2c71fba5
Source dataset
uspto-grants-2003_07
Patent number
US06589997B2

Reaction notes

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