Water → HCID 69995933, compound

Participants

Reaction Steps

A clear solution of stannous chloride dihydrate (0.84 g, 3.72 mmol) in DMF (4ml) was added to a solution of 4-[benzyl-(2-nitrophenyl)amino]phthalic acid dimethyl ester (195 mg, 0.47 mmol) in DMF (4ml) and stirred for 3 hours at room temperature. The reaction mixture was poured into water and extracted with ethyl acetate (2×25 ml). The collected organic phases was washed with water (3×25 ml), dried over magnesium sulphate, and evaporated to dryness in vacuo to give 4-[(2-aminophenyl)benzylamino]phthalic acid dimethyl ester as a slightly coloured oil (yield: 180 mg (100%)).

Provenance & Evidence