HCID 18506108, compound → HCID 18506159, compound

HRID 1357387Notes

Reaction equation

HRID 1357387 reaction equation
[N+](C1C=C(C=CC=1)C(NC1C=CC=CC=1OC1C=C([P:19](=[O:22])([OH:21])[OH:20])C=CC=1)=O)([O-])=O.C(OP([C:38]1[CH:43]=[CH:42][CH:41]=[C:40]([O:44][C:45]2[CH:50]=[CH:49][CH:48]=[CH:47][C:46]=2[NH:51][C:52](=[O:62])[C:53]2[CH:58]=[CH:57][CH:56]=[C:55]([N+:59]([O-:61])=[O:60])[CH:54]=2)[CH:39]=1)(=O)OCC)C>>[N+:59]([C:55]1[CH:54]=[C:53]([CH:58]=[CH:57][CH:56]=1)[C:52]([NH:51][C:46]1[CH:47]=[CH:48][CH:49]=[CH:50][C:45]=1[O:44][C:40]1[CH:39]=[CH:38][C:43]([P:19](=[O:20])([OH:22])[OH:21])=[CH:42][CH:41]=1)=[O:62])([O-:61])=[O:60]

Participants

3

Reactant 2

HCID 18506108HCID 18506108, compound2×HCID 86589710HCID 86589710, compound

Product 1

HCID 18506159HCID 18506159, compound

Procedure

{3-[2-(3-Nitrobenzoylamino)phenoxyl]phenyl}phosphonic acid (Compound 145) from {3-[2-(3-nitrobenzoylamino)phenoxy]phenyl}phosphonic acid diethyl ester (110 mg, 0.234 mmol) (yield: 64 mg white crystals (66%)). Mp: 120.4-122.4° C. LC/MS: m/e 415 (M+1).

Sources & evidence

ORD record
ord-15e9046d9f394506a90da594dbf30597
Source dataset
uspto-grants-2003_07
Patent number
US06590118B1

Reaction notes

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