Benzoyl chloride, 3-nitro- → HCID 18506156, compound

Participants

Reaction Steps

2-[3,4-Bis-(1-benzyl-1H-tetrazol-5-yl)phenoxy]phenylamine (37 mg, 0.07 mmol) and TEA (19 mg, 0.18 mmol) were mixed in acetone (10 ml), and 3-nitrobenzoyl chloride (15 mg, 0.08 mmol) was added. The reaction mixture was stirred for 120 hours at room temperature. The reaction mixture was evaporated in vacuo to an oil. The oil was purified on a silica column with methylene chloride/methanol (39:1) as eluent. The title compound was isolated as yellow oil (yield: 30 mg (62%). 1H-NMR (CDCl3 in ppm): 5.6 (4H,2xs); 7.0 (1H,d,d); 7.15 (1H,d,d); 7.2 (1H,d,d); 7.25-7.4 (11H,m); 7.6 (1H,d,d); 7.73 (1H,d); 7.9 (1H,d); 8.1 (1H,d,d); 8.35 (1H,d,d); 8.45 (1H,broad s); 8.55 (1H,d,d); 8.7 (1H,d,d).

Provenance & Evidence