(4-Nitrophenyl)acetate → HCID 69532418, 화합물

참여 물질

반응 단계

0.73 g (2.0 mmol) of methyl L-tyrosyl-L-valyl-L-alaninate (Example 1, Step A3) is dissolved in 5 ml of dimethylformamide, then 0.4 g (2.2 mmol) of p-nitro-phenyl-acetate is added. The reaction mixture is stirred at room temperature overnight then is evaporated at a pressure of 2.0-2.5 kPa. The residue is dissolved in 15 ml of ethyl acetate, the solution is washed with 3×5 ml of water, 5 ml of 1 M KHSO4 and 3×5 ml of water, then dried over anhydrous sodium sulfate and evaporated at a pressure of 2.0-2.5 kPa. The residue is rubbed with diethyl ether, filtered, washed with diethyl ether and dried in a vacuum desiccator.

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