(1,1'-Biphenyl)-4-methanol → HCID 18186833, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure of example 4, step 1 starting from 2,6-dichloropyrazine (444 mg, 3.00 mmol),p-phenylbenzyl alcohol (607 mg, 3.30 mmol) and NaH (55% in mineral oil, 144 mg, 3.30 mmol). Recrystallization from hexane gave 0.55 g (88%) of the title compound: mp 86-87° C. MS m/z: 297 (M+H)+. Anal. (C17H13ClN2O) C, H, N.

Provenance & Evidence