Piperazine → HCID 18186810, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure of example 50, step 2, starting from 2-chloro-6-[(3-phenoxybenzyl)oxy]pyrazine (1.99 g, 6.36 mmol; obtained according to the procedure of example 50, step 1, starting from 3-phenoxybenzyl alcohol), piperazine (1.94 g, 22.5 mmol) and K2CO3 (0.88 g, 6.4 mmol). The yield of the title compound was 1.58 g (69%) which was obtained as an oil. Purity 100% (HPLC). MS m/z 363 (M+H)+. HRMS m/z calcd for C21H22N4O2 (M)+ 362.1743, found 362.1739.

Provenance & Evidence