HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Morpholinobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-(Morpholin-4-yl)benzoic acid | HCID 2795549 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Morpholinobenzoyl chloride | HCID 22057972 | — |
Reaction Steps
Oxalyl chloride (0.14 ml) was added to a solution of 3-morpholinobenzoic acid (0.28 g) in methylene chloride (10 ml) which contained N,N-dimethylformamide (2 drops). The reaction mixture was stirred for 18 hours at ambient temperature. The mixture was evaporated and azeotroped with toluene to yield 3-morpholinobenzoyl chloride (0.3 g); M/z M+H+ 222.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06593333B1 |
| Source dataset | uspto-grants-2003_07 |
| ORD ID | ord-2251e0aa04d6458e8f6e2dcbba810c83 |
| Source note | uspto-grants-2003_07 |