HCID 69987608, compound → HCID 69987615, compound

HRID 1357816Notes

Reaction equation

HRID 1357816 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][CH2:10][C:11]2[N:15]([CH3:16])[C:14]3[CH:17]=[CH:18][C:19]([C:21]([CH2:30][NH2:31])([C:23]([N:25]4[CH2:29][CH2:28][CH2:27][CH2:26]4)=[O:24])[CH3:22])=[CH:20][C:13]=3[N:12]=2)=[CH:5][CH:4]=1)#[N:2].Br[CH2:33][C:34]([O:36][CH2:37][CH3:38])=[O:35].C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([NH:9][CH2:10][C:11]2[N:15]([CH3:16])[C:14]3[CH:17]=[CH:18][C:19]([C:21]([CH2:30][NH:31][CH2:33][C:34]([O:36][CH2:37][CH3:38])=[O:35])([C:23]([N:25]4[CH2:29][CH2:28][CH2:27][CH2:26]4)=[O:24])[CH3:22])=[CH:20][C:13]=3[N:12]=2)=[CH:7][CH:8]=1)#[N:2]

Participants

4

Reactant 2

HCID 69987608HCID 69987608, compoundHCID 131723981HCID 131723981, compound

Product 1

HCID 69987615HCID 69987615, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Prepared analogously to Example 1k from 2-(4-cyanophenylamino-methyl)-1-methyl-5-[1-aminomethyl-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole and ethyl bromoacetate/potassium carbonate in acetone.

Sources & evidence

ORD record
ord-3a50bf9abe284e32b74eba6592422a28
Source dataset
uspto-grants-2003_07
Patent number
US06593355B2

Reaction notes

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