tert-Butoxy bis(dimethylamino)methane → 4-(3-Dimethylamino-2-phenyl-acryloyl)-1H-pyrrole-2-carboxylic acid benzylamide

Beteiligte Stoffe

Reaktionsschritte

To a solution of compound 2 (1 equivalent) in THF, at ambient temperature, was added (Me2N)2CHOt-Bu (3 equivalents). After 24 hours, the solvent was evaporated and the crude product 3 was utilized without purification. 1H NMR (CDCl3) δ 4.4 (s, 2H), 4.8 (s, NH), 6.8-7.4 (m, 13H).

Herkunft & Nachweise