HCID 69532806, compound → HCID 18188111, compound

Participants

Reaction Steps

A mixture of ethyl 6-benzyloxy-3-{4-[2-(2-o-tolylamino-benzoxazol-6-yl)-acetylamino]-phenyl}-3-hexenoate (640 mg, Reference Example 22(a)) and 10% palladium on charcoal (250 mg) in ethanol (50 mL) was hydrogenated at room temperature and pressure. After 24 hours further catalyst (200 mg) was added and the mixture again subjected to a hydrogen atmosphere for a further 24 hours. The mixture was filtered through filter-aid and the filtrate evaporated to dryness to give the title compound (460 mg) as a colourless oil.

Provenance & Evidence