Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1357984Generated: November 2, 2026

HCID 23440891, compound → HCID 12992436, compound

https://huagongshe.com/reaction/1357984

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23440891HCID 23440891—
CatalystAcetic AcidHCID 176—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 12992436HCID 1299243663%

Reaction Steps

A solution of 1-{4-(phenylmethoxy)benzyl}-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline (0.60 g, 1.38 mmol), palladium (5% wt. on activated carbon, 0.06 g), and glacial acetic acid (3 drops) in ethanol (30 mL) was stirred under hydrogen for 15 hours. The reaction was filtered and concentrated to provide the title compound (0.30 g, 63% yield): ES-MS (m/z) 346 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06593322B1
Source datasetuspto-grants-2003_07
ORD IDord-287b7f275e74406ab8766d21a3cdb6c3
Source noteuspto-grants-2003_07