HRID1358006

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc2c(c1)CCN(c1ccc(NC(C)=O)cc1)C2Cc1ccc(OCc2ccccc2)cc1

HCID23440860

未命名化合物

PRODUCTS

生成物

结构：COc1ccc2c(c1)CCN(c1ccc(NC(C)=O)cc1)C2Cc1ccc(O)cc1

HCID23440786

未命名化合物

收率 95.3%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID21873804

未命名化合物

PROCEDURE

实验过程

A solution of 2-(4-acetamidophenyl)-6-methoxy-1-[4-(phenylmethoxy)benzyl]-1,2,3,4-tetrahydroisoquinoline (0.190 g, 0.386 mmol) in 2 mL of EtOH/THF (1:1) was debenzylated with 10% Pd/C under an H2 atmosphere as described in Example 30.F to provide the title compound (0.148 g, 95% yield): ES-MS (m/z) 403 [M+H]+.