Water → HCID 178474079, compound

Participants

Reaction Steps

15.5 ml (25.2 mmol) of t-butyllithium are added dropwise at −80° C. to a solution of 2 g (8.4 mmol) of monoferrocenylacetamide in 40 ml of THF. The mixture is subsequently warmed slowly to room temperature. After stirring for one hour at room temperqture, an excess of cyclohexyldimethylchlorosilane is added [5 ml (23 mmol) of cyclohexyldimethylchlorosilane]. The mixture is poured into 100 ml of water and extracted a number of times with ether, and the combined ether phases are washed with water. Purification is carried out by means of column chromatography (eluant CH2Cl2; Al2O3).

Provenance & Evidence